2AAZ: Cryptococcus neoformans thymidylate synthase complexed with substrate and an antifolate

PDB ID: 2AAZDownload
MMDB ID: 36082
PDB Deposition Date: 2005/7/14
Updated in MMDB: 2005/12
Experimental Method:
x-ray diffraction
Resolution: 2.08  Å
Source Organism:
Similar Structures:
Biological Unit for 2AAZ: dimeric; determined by author
Molecular Components in 2AAZ
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
2'-DEOXYURIDINE 5'-MONOPHOSPHATE2'-DEOXYURIDINE 5'-MONOPHOSPHATE
2
2
10-PROPARGYL-5,8-DIDEAZAFOLIC ACID10-PROPARGYL-5,8-DIDEAZAFOLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303